Technical Information
Kotthaus, J., Schade, D., Muschick, N., Beitz, E.,Clement, B.: (2008), “Structure-activity relationship of novel and known inhibitors of dimethylaminohydrolase-1, alkenyl-amidines as new leads” Bioorg. Med. Chem., 16, 10205-10209
Bretscher, L.E., Li, H., Poulos, T.L., Griffith, O.W.: (2003), “Structural characterization and kinetics of nitric oxide synthase inhibition by novel N5-(Iminoalkyl)- and N5-(Iminoalkenyl)-ornithines” J. Biol. Chem., 278, 46789-46797
Griffith, O.W., Babu, B.R.: (2000), “N5-(1-Imino-3-butenyl)-L-ornithine and Related Compounds and Use Thereof” U.S. Patent No. 6,127,420
Babu, B.R., Frey, C., Griffith, O.W.: (1999), “L-Arginine Binding to Nitric Oxide Synthase: The Role of H-Bonds to the Non-Reactive Guanidinium Nitrogens” J. Biol. Chem., 274, 25218-25226
Babu, B.R., Griffith, O.W.: (1998), “N5-(1-Imino-3-butenyl)-L-ornithine: A Neuronal Isoform Selective Mechanism-Based Inactivator of Nitric Oxide Synthase. J. Biol. Chem., 273, 8882-8889
Babu, B.R., Vaz, A.D.N.: (1997), “1,2,3-Thiadiazole: A Novel Heterocyclic Heme Ligand for the Design of Cytochrome P450 Inhibitors” Biochemistry, 36, 7209-7216
